Thursday, 26 March 2015

Abnormally High Vitamin B6(Pyridoxine) Blood Plasma Test

This is a phenomenon that i discovered many years ago when i was looking into bio-chemical factors that were causing my chronic health problems.

Something that regularly came up in vitamin panel blood work was a high vitamin b6(pyridoxine) blood serum reading, despite having not consumed any vitamin b6 containing supplements or fortified foods.

There is actually some scientific research which documents this high vitamin b6 blood serum level in children with Autistic spectrum disorders, despite having not supplemented.  Full study can be viewed at - Abnormally high plasma levels of vitamin B6 in children with autism not taking supplements compared to controls not taking supplements.

The study concluded the reason for the high vitamin b6(pyridoxine) level was due to impaired conversion to its active forms such as PLP and P5P.

Conversion of pyridoxine to active P5P requires healthy levels of other nutrients such as vitamin B2(riboflavin) and magnesium.

These individuals may benefit from consuming an Active Vitamin B Complex, which contains the co-enzyme and "active" forms of these B-complex vitamins.

A possible genetic inability to convert pyridoxine to active P5P(Pyridoxal-5-Phosphate) may be common in individuals of European and Irish descent.

Test below was done about 7-8 years ago.  (Click to view full-size image).

Anyway i thought i would do a blog post on this topic, incase it was of help to anyone else facing similar issues.

Id love to hear from others who had a high vitamin B6(pyridoxine) blood plasma reading despite having consumed no vitamin b6 supplements.